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Long-Term Outcomes after Radiosurgery for Acoustic Neuromas NEJM 339:1426-1433,1471, Kondziolka,D.,et al, 1998 See this aricle in Pubmed Article Abstract The rate of tumor control (with no resection required) was 98%. One hundred tumors (62%) became smaller, 53 (33%) remained unchanged in size and 9 (6%) became slightly larger. Resection was performed in four patients (2%) within four years after radiosurgery. Normal facial function was preserved in 79% of the patients after 5 years (House-Brackman grade 1) and normal trigeminal function was preserved in 73%. Fifty-one percent of the patients had no change in hearing ability. No new neurologic defects appeared more than 28 months after radiosurgery. An outcomes questionnaire was returned by 115 patients (77% of the 149 patients still living). Fifty-four of these patients (47%) were employed at the time of radiosurgery and 37 (69%) remained so. Radiosurgery was believed to have been successful by all 30 patients who had undergone surgery previously and by 81 (95%) of the 85 who had not. Thirty-six of the 115 patients (31%) described at least one complication which resolved in 56% of those cases. Radiosurgery can provide long term control of acoustic neuromas while preserving neurologic function.

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